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| First Round Draft Pick History |
| 1 | 4 | 4 | 2021 | Annual Draft | OF | Adolis | Garcia | MLB |
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| 1 | 4 | 4 | 2021 | 28 Man Draft | P | Johnny | Cueto | MLB |
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| 1 | 2 | 2 | 2020 | 28 Man Draft | 1B | Matt | Adams | MLB |
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| 1 | 3 | 3 | 2019 | Rookie Draft | SP | Miles | Mikolas | MLB |
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| 1 | 2 | 2 | 2018 | Rookie Draft | SP | Jakob | Junis | MLB |
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| 1 | 4 | 4 | 2017 | Rookie Draft | OF | Hunter | Renfroe | MLB |
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| 1 | 9 | 9 | 2016 | Rookie Draft | OF | Odubel | Herrera | MLB |
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| 1 | 5 | 5 | 2013 | Rookie Draft | OF | Norichika | Aoki | MLB |
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| 1 | 12 | 12 | 2012 | Rookie Draft | 2B | Jemile | Weeks | MLB |
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| 1 | 5 | 5 | 2011 | Rookie Draft | SP | Alexi | Ogando | MLB |
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| 1 | 15 | 15 | 2010 | Rookie Draft | SS | Alex | Gonzalez | MLB |
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| 1 | 3 | 3 | 2009 | Rookie Draft | OF | Denard | Span | MLB |
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| 1 | 8 | 8 | 2008 | Rookie Draft | OF | Rick | Ankiel | MLB |
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| 1 | 7 | 7 | 2007 | Rookie Draft | SP | Anibal | Sanchez | MLB |
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| 1 | 20 | 20 | 2006 | Rookie Draft | OF | Jason | Repko | MLB |
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| 1 | 20 | 20 | 2005 | Rookie Draft | C | Yadier | Molina | MLB |
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| 1 | 11 | 11 | 2004 | Rookie Draft | SP | Juan | Dominguez | MLB |
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| Complete Draft History |
| 1 | 4 | 4 | 2021 | Annual Draft | OF | Adolis | Garcia | MLB |
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| 1 | 4 | 4 | 2021 | 28 Man Draft | P | Johnny | Cueto | MLB |
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| 2 | 4 | 28 | 2021 | 28 Man Draft | P | Rafael | Montero | MLB |
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| 2 | 4 | 28 | 2021 | Annual Draft | P | Keegan | Akin | MLB |
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| 3 | 4 | 52 | 2021 | 28 Man Draft | 1B | Matt | Adams | MLB |
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| 4 | 4 | 76 | 2021 | Annual Draft | OF | Franchy | Cordero | MLB |
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| 5 | 4 | 100 | 2021 | Annual Draft | P | Wil | Crowe | MLB |
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| 6 | 4 | 124 | 2021 | Annual Draft | P | Travis | Lakins | MLB |
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| 7 | 4 | 148 | 2021 | Annual Draft | P | Joely | Rodriguez | MLB |
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| 8 | 4 | 172 | 2021 | Annual Draft | P | Ryan | Sherriff | MLB |
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| 9 | 4 | 196 | 2021 | Annual Draft | P | Taylor | Hearn | MLB |
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| 10 | 4 | 220 | 2021 | Annual Draft | P | Geoff | Hartlieb | MLB |
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| 1 | 2 | 2 | 2020 | 28 Man Draft | 1B | Matt | Adams | MLB |
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| 2 | 2 | 26 | 2020 | 28 Man Draft | P | Steven | Brault | MLB |
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| 2 | 2 | 26 | 2020 | Annual Draft | 3B+ | Nick | Solak | MLB |
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| 3 | 2 | 50 | 2020 | Annual Draft | OF | Harold | Ramirez | MLB |
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| 3 | 2 | 50 | 2020 | 28 Man Draft | P | Zack | Godley | MLB |
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| 4 | 2 | 74 | 2020 | Annual Draft | P | Jacob | Waguespack | MLB |
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| 5 | 2 | 98 | 2020 | Annual Draft | SS | Richie | Martin | MLB |
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| 6 | 2 | 122 | 2020 | Annual Draft | OF | Keon | Broxton | MLB |
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| 7 | 2 | 146 | 2020 | Annual Draft | 3B+ | Jung Ho | Kang | MLB |
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| 8 | 2 | 170 | 2020 | Annual Draft | 1B+ | Sam | Travis | MLB |
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| 9 | 2 | 194 | 2020 | Annual Draft | P | Justin | Shafer | MLB |
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| 10 | 2 | 218 | 2020 | Annual Draft | P | Josh | Osich | MLB |
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| 1 | 3 | 3 | 2019 | Rookie Draft | SP | Miles | Mikolas | MLB |
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| 2 | 3 | 27 | 2019 | Rookie Draft | SS | Yairo | Munoz | MLB |
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| 3 | 3 | 51 | 2019 | Rookie Draft | OF | Daniel | Palka | MLB |
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| 4 | 3 | 75 | 2019 | Rookie Draft | RP | Chaz | Roe | MLB |
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| 5 | 3 | 99 | 2019 | Rookie Draft | RP | Justin | Miller | MLB |
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| 6 | 3 | 123 | 2019 | Rookie Draft | SP | Ian | Kennedy | MLB |
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| 7 | 3 | 147 | 2019 | Rookie Draft | RP | Brad | Ziegler | MLB |
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| 1 | 2 | 2 | 2018 | Rookie Draft | SP | Jakob | Junis | MLB |
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| 2 | 3 | 27 | 2018 | Rookie Draft | RP | John | Brebbia | MLB |
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| 3 | 2 | 50 | 2018 | Rookie Draft | RP | Wandy | Peralta | MLB |
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| 4 | 3 | 75 | 2018 | Rookie Draft | 3B | Deven | Marrero | MLB |
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| 5 | 2 | 98 | 2018 | Rookie Draft | SP | James | Shields | MLB |
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| 6 | 3 | 123 | 2018 | Rookie Draft | 2B | Max | Moroff | MLB |
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| 7 | 2 | 146 | 2018 | Rookie Draft | SP | Derek | Holland | MLB |
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| 8 | 3 | 171 | 2018 | Rookie Draft | SP | Ubaldo | Jimenez | MLB |
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| 9 | 2 | 194 | 2018 | Rookie Draft | SP | Dylan | Covey | MLB |
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| 10 | 3 | 219 | 2018 | Rookie Draft | SP | Buck | Farmer | MLB |
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| 1 | 4 | 4 | 2017 | Rookie Draft | OF | Hunter | Renfroe | MLB |
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| 2 | 4 | 28 | 2017 | Rookie Draft | 1B | Dae-Ho | Lee | MLB |
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| 2 | 24 | 48 | 2017 | Rookie Draft | OF | Taylor | Motter | MLB |
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| 3 | 4 | 52 | 2017 | Rookie Draft | OF | Brian | Goodwin | MLB |
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| 5 | 4 | 100 | 2017 | Rookie Draft | RP | Jose | Leclerc | MLB |
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| 6 | 4 | 124 | 2017 | Rookie Draft | SP | Wily | Peralta | MLB |
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| 7 | 4 | 148 | 2017 | Rookie Draft | SS | Cristhian | Adames | MLB |
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| 7 | 24 | 168 | 2017 | Rookie Draft | 1B | Byung Ho | Park | MLB |
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| 8 | 4 | 172 | 2017 | Rookie Draft | OF | Tyler | Goeddel | MLB |
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| 9 | 4 | 196 | 2017 | Rookie Draft | C | Eric | Fryer | MLB |
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| 10 | 4 | 220 | 2017 | Rookie Draft | SP | John | Lamb | MLB |
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| 1 | 9 | 9 | 2016 | Rookie Draft | OF | Odubel | Herrera | MLB |
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| 2 | 9 | 33 | 2016 | Rookie Draft | OF | Delino | DeShields | MLB |
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| 3 | 9 | 57 | 2016 | Rookie Draft | 3B | Tyler | Saladino | MLB |
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| 4 | 9 | 81 | 2016 | Rookie Draft | 3B | Giovanny | Urshela | MLB |
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| 5 | 9 | 105 | 2016 | Rookie Draft | SP | Jerome | Williams | MLB |
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| 6 | 9 | 129 | 2016 | Rookie Draft | SP | Matt | Boyd | MLB |
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| 7 | 9 | 153 | 2016 | Rookie Draft | C | Jesus | Sucre | MLB |
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| 8 | 9 | 177 | 2016 | Rookie Draft | SP | Sean | O'Sullivan | MLB |
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| 9 | 9 | 201 | 2016 | Rookie Draft | RP | Matt | Bush | MIN |
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| 10 | 9 | 225 | 2016 | Rookie Draft | C | Hector | Sanchez | MLB |
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| 2 | 2 | 26 | 2015 | Rookie Draft | 3B | Charlie | Culberson | MLB |
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| 3 | 2 | 50 | 2015 | Rookie Draft | 3B | Kris | Negron | MLB |
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| 4 | 2 | 74 | 2015 | Rookie Draft | SS | Jorge | Polanco | MLB |
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| 5 | 2 | 98 | 2015 | Rookie Draft | SS | Gregorio | Petit | MLB |
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| 6 | 2 | 122 | 2015 | Rookie Draft | SS | Miguel | Rojas | MLB |
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| 7 | 2 | 146 | 2015 | Rookie Draft | OF | Terrance | Gore | MLB |
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| 8 | 2 | 170 | 2015 | Rookie Draft | RP | Mario | Hollands | MLB |
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| 9 | 2 | 194 | 2015 | Rookie Draft | 2B | Chris | Valaika | MLB |
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| 10 | 2 | 218 | 2015 | Rookie Draft | SP | Yohan | Flande | MLB |
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| 1 | 5 | 5 | 2013 | Rookie Draft | OF | Norichika | Aoki | MLB |
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| 2 | 6 | 30 | 2013 | Rookie Draft | OF | Justin | Maxwell | MLB |
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| 3 | 5 | 53 | 2013 | Rookie Draft | C | Chris | Snyder | MLB |
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| 4 | 6 | 78 | 2013 | Rookie Draft | C | Rob | Brantly | MLB |
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| 5 | 5 | 101 | 2013 | Rookie Draft | SP | Will | Smith | MLB |
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| 6 | 6 | 126 | 2013 | Rookie Draft | 2B | Rougned | Odor | MIN |
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| 7 | 5 | 149 | 2013 | Rookie Draft | SP | Hector | Noesi | MLB |
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| 8 | 6 | 174 | 2013 | Rookie Draft | OF | Jordan | Danks | MLB |
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| 9 | 5 | 197 | 2013 | Rookie Draft | RP | Hisanori | Takahashi | MLB |
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| 10 | 6 | 222 | 2013 | Rookie Draft | C | Mike | Nickeas | MLB |
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| 1 | 12 | 12 | 2012 | Rookie Draft | 2B | Jemile | Weeks | MLB |
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| 2 | 12 | 36 | 2012 | Rookie Draft | OF | Tony | Campana | MLB |
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| 3 | 12 | 60 | 2012 | Rookie Draft | 3B | Michael | Martinez | MLB |
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| 4 | 12 | 84 | 2012 | Rookie Draft | P | Anthony | Swarzak | MLB |
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| 4 | 23 | 95 | 2012 | Rookie Draft | P | Aneury | Rodriguez | MLB |
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| 5 | 12 | 108 | 2012 | Rookie Draft | C | Rene | Rivera | MLB |
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| 6 | 12 | 132 | 2012 | Rookie Draft | P | Yoshinori | Tateyama | MLB |
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| 7 | 12 | 156 | 2012 | Rookie Draft | 3B | Mike | Olt | MIN |
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| 8 | 12 | 180 | 2012 | Rookie Draft | P | Jason | Isringhausen | MLB |
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| 9 | 12 | 204 | 2012 | Rookie Draft | OF | Michael | Choice | MIN |
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| 10 | 12 | 228 | 2012 | Rookie Draft | C | Manuel | Pina | MLB |
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| 1 | 5 | 5 | 2011 | Rookie Draft | SP | Alexi | Ogando | MLB |
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| 2 | 4 | 28 | 2011 | Rookie Draft | C | John | Jaso | MLB |
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| 3 | 5 | 53 | 2011 | Rookie Draft | RP | Brad | Thomas | MLB |
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| 4 | 4 | 76 | 2011 | Rookie Draft | C | Jason | Castro | MLB |
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| 5 | 5 | 101 | 2011 | Rookie Draft | RP | Sam | Demel | MLB |
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| 6 | 4 | 124 | 2011 | Rookie Draft | RP | Randy | Choate | MLB |
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| 7 | 5 | 149 | 2011 | Rookie Draft | RP | David | Herndon | MLB |
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| 8 | 4 | 172 | 2011 | Rookie Draft | RP | Alex | Burnett | MLB |
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| 8 | 18 | 186 | 2011 | Rookie Draft | RP | Eddie | Bonine | MLB |
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| 9 | 5 | 197 | 2011 | Rookie Draft | SP | Brian | Burres | MLB |
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| 10 | 4 | 220 | 2011 | Rookie Draft | C | Mike | Redmond | MLB |
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| 1 | 15 | 15 | 2010 | Rookie Draft | SS | Alex | Gonzalez | MLB |
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| 2 | 15 | 39 | 2010 | Rookie Draft | C | Jason | Jaramillo | MLB |
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| 3 | 15 | 63 | 2010 | Rookie Draft | SP | Jason | Berken | MLB |
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| 4 | 15 | 87 | 2010 | Rookie Draft | RP | Clay | Zavada | MLB |
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| 5 | 15 | 111 | 2010 | Rookie Draft | RP | Chris | Ray | MLB |
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| 6 | 15 | 135 | 2010 | Rookie Draft | RP | Elmer | Dessens | MLB |
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| 7 | 15 | 159 | 2010 | Rookie Draft | RP | Koji | Uehara | MLB |
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| 8 | 15 | 183 | 2010 | Rookie Draft | RP | Doug | Mathis | MLB |
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| 9 | 15 | 207 | 2010 | Rookie Draft | SP | Rich | Hill | MLB |
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| 10 | 15 | 231 | 2010 | Rookie Draft | 2B | Josh | Barfield | MLB |
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| 1 | 3 | 3 | 2009 | Rookie Draft | OF | Denard | Span | MLB |
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| 2 | 3 | 27 | 2009 | Rookie Draft | SS | Mike | Aviles | MLB |
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| 3 | 3 | 51 | 2009 | Rookie Draft | SP | Mike | Hampton | MLB |
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| 4 | 3 | 75 | 2009 | Rookie Draft | RP | Darren | O'Day | MLB |
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| 5 | 3 | 99 | 2009 | Rookie Draft | RP | Ramon A. | Ramirez | MLB |
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| 6 | 3 | 123 | 2009 | Rookie Draft | RP | Doug | Mathis | MLB |
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| 7 | 3 | 147 | 2009 | Rookie Draft | SP | Greg | Reynolds | MLB |
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| 8 | 3 | 171 | 2009 | Rookie Draft | OF | Julio | Borbon | MIN |
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| 9 | 3 | 195 | 2009 | Rookie Draft | RP | Wesley | Wright | MLB |
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| 10 | 3 | 219 | 2009 | Rookie Draft | OF | So | Taguchi | MLB |
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| 1 | 8 | 8 | 2008 | Rookie Draft | OF | Rick | Ankiel | MLB |
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| 2 | 8 | 32 | 2008 | Rookie Draft | SP | Matt | Chico | MLB |
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| 2 | 22 | 46 | 2008 | Rookie Draft | C | JR | Towles | MLB |
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| 3 | 8 | 56 | 2008 | Rookie Draft | RP | Lance | Broadway | MLB |
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| 3 | 16 | 64 | 2008 | Rookie Draft | SP | Brian | Burres | MLB |
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| 4 | 8 | 80 | 2008 | Rookie Draft | OF | Ryan | Raburn | MLB |
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| 5 | 8 | 104 | 2008 | Rookie Draft | OF | Brandon | Moss | MLB |
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| 6 | 8 | 128 | 2008 | Rookie Draft | OF | Shelley | Duncan | MLB |
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| 7 | 8 | 152 | 2008 | Rookie Draft | RP | A.J. | Murray | MLB |
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| 8 | 8 | 176 | 2008 | Rookie Draft | RP | Guillermo | Rodriguez | MLB |
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| 9 | 8 | 200 | 2008 | Rookie Draft | C | Koyie | Hill | MLB |
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| 10 | 8 | 224 | 2008 | Rookie Draft | OF | Jason | Ellison | MLB |
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| 1 | 7 | 7 | 2007 | Rookie Draft | SP | Anibal | Sanchez | MLB |
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| 2 | 7 | 31 | 2007 | Rookie Draft | SS | Erick | Aybar | MLB |
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| 3 | 7 | 55 | 2007 | Rookie Draft | RP | Wes | Littleton | MLB |
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| 4 | 7 | 79 | 2007 | Rookie Draft | RP | Nick | Masset | MLB |
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| 5 | 7 | 103 | 2007 | Rookie Draft | SP | Eric | Hurley | MIN |
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| 6 | 7 | 127 | 2007 | Rookie Draft | RP | Clay | Condrey | MLB |
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| 7 | 7 | 151 | 2007 | Rookie Draft | 1B | Eric | Munson | MLB |
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| 8 | 7 | 175 | 2007 | Rookie Draft | RP | Jon | Adkins | MLB |
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| 9 | 7 | 199 | 2007 | Rookie Draft | OF | Kevin | Thompson | MLB |
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| 10 | 7 | 223 | 2007 | Rookie Draft | SP | Ben | Hendrickson | MLB |
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| 1 | 20 | 20 | 2006 | Rookie Draft | OF | Jason | Repko | MLB |
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| 2 | 19 | 43 | 2006 | Rookie Draft | 3B | Willy | Aybar | MLB |
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| 3 | 20 | 68 | 2006 | Rookie Draft | RP | Scott | Munter | MLB |
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| 4 | 19 | 91 | 2006 | Rookie Draft | OF | Freddy | Guzman | MIN |
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| 5 | 20 | 116 | 2006 | Rookie Draft | C | Kelly | Shoppach | MLB |
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| 6 | 19 | 139 | 2006 | Rookie Draft | SP | Scott | Feldman | MLB |
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| 7 | 20 | 164 | 2006 | Rookie Draft | RP | Vic | Darensbourg | MLB |
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| 8 | 19 | 187 | 2006 | Rookie Draft | OF | Chris | Magruder | MLB |
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| 9 | 20 | 212 | 2006 | Rookie Draft | SP | C.J. | Wilson | MLB |
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| 10 | 19 | 235 | 2006 | Rookie Draft | SP | Sean | Henn | MLB |
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| 1 | 20 | 20 | 2005 | Rookie Draft | C | Yadier | Molina | MLB |
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| 2 | 19 | 43 | 2005 | Rookie Draft | RP | Mike | Adams | MLB |
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| 3 | 20 | 68 | 2005 | Rookie Draft | RP | Doug | Brocail | MLB |
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| 4 | 19 | 91 | 2005 | Rookie Draft | SP | John | Danks | MIN |
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| 6 | 19 | 139 | 2005 | Rookie Draft | RP | John | Wasdin | MLB |
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| 7 | 20 | 164 | 2005 | Rookie Draft | SP | Edinson | Volquez | MIN |
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| 8 | 19 | 187 | 2005 | Rookie Draft | OF | Chad | Allen | MLB |
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| 9 | 20 | 212 | 2005 | Rookie Draft | 2B | Joey | Thurston | MLB |
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| 10 | 19 | 235 | 2005 | Rookie Draft | SP | Rocky | Biddle | MLB |
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| 1 | 11 | 11 | 2004 | Rookie Draft | SP | Juan | Dominguez | MLB |
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| 2 | 10 | 34 | 2004 | Rookie Draft | SP | R.A. | Dickey | MLB |
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| 3 | 9 | 57 | 2004 | Rookie Draft | RP | Frank | Francisco | MIN |
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| 4 | 11 | 83 | 2004 | Rookie Draft | 1B | Adrian | Gonzalez | MIN |
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| 5 | 10 | 106 | 2004 | Rookie Draft | RP | Cal | Eldred | MLB |
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| 6 | 9 | 129 | 2004 | Rookie Draft | RP | Wil | Ledezma | MLB |
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| 7 | 11 | 155 | 2004 | Rookie Draft | 2B | Keith | Lockhart | MLB |
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